Elevated ACTH but low Cortisol
Routine bloodwork is showing high ACTH-140 pg/mL but a Cortisol saliva test (4 sample) shows, what appears to be, low cortisol levels--8AM-.23 mcg/dL, 12PM-.05mcg/dL, 4PM- .03 mcg/mL, 8PM-.03 mcg/dL Can cortisol be too low (possible Addison's without symptoms? Can any of this be caused by daily exercise, daily cold plunge or a moderate to low carbohydrate diet? When should I see an endocrinologist? Thanks!
Glaucoma Treatment
I was diagnosed with Open Angle, Normal Tension in 2004. I’ve been very blessed to still have 20/20 vision with little peripheral vision loss. Only recently has there been an eye drop for my type of glaucoma and I just started taking. I’ve had drain stents & SLT surgery. My last visit showed more optic nerve damage. I’m interested in trying some non-glaucoma FDA approved drugs. I’ve researched acrobose, metformin and rampamycin. There is little concrete evidence that any of these drugs will help. I’m measuring the risk/reward ratio. I’m a very healthy & fit 54 year old male. With no intervention I will probably be totally blind in under 5 to 10 years. I am a High Intensity Trainer too. Been in the HIT community since the 1980’s. I only used BFR(Blood Flow Restriction) on my clients or myself to help rehab from injuries & limitations. Since about 2010 I’ve used it to help hopefully produce more BDNF & VEG-F to possibly help slow the nerve damage to my optic nerves. Thoughts on this. Any suggestions if you were in my shoes?