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1991 Brazil MP4/6 Senna

Is this the greatest of Senna’s victories and will Peter please buy this car to drive at COTA? https://apple.news/A-C_y9bifRSaYtdbkyYxvRg

Hormone replacement therapy

I am a medical physicianand I am confused about the safety profile about hormone replacement therapy for menopausal women

Is Lisdexamfetamine worth the blood pressure increase?

I have been diagnosed with adult ADHD and I am taking Lisdexamfetamine. It has helped my attention and productivity at work but it does raise my blood pressure to right as the normal level or slightly above (118-122/78-82), while normally i sit below. How damaging is the increase in blood pressure if you are still around normal range? I'm trying to weigh the benefits of the increased productivity vs the long-term risk of an elevated blood pressure.

Effect of statins on gut microbiome

Did you see article in Cell metabolism on the mechanism of elevated blood glucose due to statins effect on gut microbiome and GLP1 secretion?

Exercising with a VR Headset

Would you consider exercising with a VR headset, such as using the Supernatural app, to be useful in building muscle, getting quality cardiovascular exercise, and even exercising our brains by having to follow the cues and hit the targets?

Lead in protein

I have been using Jacks Fuel protein power since Jacko was on the podcast but saw the Consumer Reports article about lead in protein powered and some Jacko products were listed. How should I think about this? What protein power does Peter use?

Asymptomatic atrial fibrillation

I was an athletic healthy seventy six year old ready for a morning bike ride when I suddenly collapsed from a right middle cerebral artery stroke. I am still puzzled as to why this happened?

Full Body MRI

What's Peter view on Full Body MRI? Cost/Benefit? If positive - how often etc. Thnx

Taking complete amino acid like Perfect Aminos brand

is there value in taking amino acids in terms of recovery after resistance training or when fasting to keep up protein intake, and to continue exercising?

GLP One question

With the introduction of sensors that measure blood sugar without a prescription for a Zepbound patient with no diagnosis of diabetes with a normal A1C did you think this level of monitoring?

Percussion-massage guns

Are percussion-massage guns effective at eliminating soreness and and preparing you for your next workout, or are the benefits all just marketing?

Can Too Much Protein Be A Problem?

Is it possible to consume too much protein? Recently, my doctor encouraged me to reduce my carbohydrate intake (130 grams per day) and increase my protein intake (100 grams per day). I am a 56-year-old female, weighing 120 pounds. I started having heartburn and indigestion daily. This is something I have never experienced before, and I am unsure if it was due to this or just a coincidence.

Pediatric + Longevity

How would you approach pediatrics; how would your approach to health span and longevity inform decisions about exercise, nutrition, sleep, education of a 1 to 5 year old

HOMA2-BETA index

Hi, I'm wondering how relevant HOMA2-BETA results are for a person with low level of fasting insulin (below the range)? I got between 40s and 70s HOMA2BETA, 0.5 HOMA2IR A and 250-300 HOMA2S (two tests taken about 3 months apart, with the second having lower level of fasting insulin and a bit higher FBG (4.7 vs. 4.9 mmol/l). I eat in 10-12 hrs window, no dinner, lower carb (below 100 net carbs a day), active (walking, kettlebell training at home, resistance band, bodyweight, occasional HIIT...). Pancreas antibodies are negative (but not zero), anti-TG elevated (so Hashimoto's). Extended ogtt (5h) indicate diabetes (60min at above 11mmol/l, but 7.3 at 120 min and last 3 measurements at 3.5mmol/l. HbA1C is 5.1-5.3. What to make of it? If not for an AMA, may be sth to discuss in one of future episodes on diabetes, glucose intolerance, insulin resistance etc.). Thanks, and keep up the good work!

What is best source of chicken, eggs, meat and fish?

I know organic chicken, meat, eggs etc are good sources of protein. Is organic chicken, eggs and meat from Costco is good enough or is there a better source that is equally affordable but better in quality? Is Amish chicken and egg are good quality?

Is cold-inducible RNA-binding protein CIRBP the next Klotho?

Please comment on the finding of a protein in bowhead whales that repairs double-stranded DNA breaks and thus prevents cancer: https://www.nature.com/articles/s41586-025-09694-5

Infrared vs Dry Sauna

Thoroughly enjoyed your podcast episode with Rhonda Patrick! You discussed that infrared saunas require you to stay in longer to get the same benefits as dry sauna. But the age-old question is "How much longer?" Rhonda said she used her parents' infrared sauna, but had to "stay in there much longer." What metric did she use to determine the length of her infrared session? Skin temp? It seems to be universally understood that 20min in a dry sauna at ~180° is good. And then the follow-up is usually "infrared saunas require longer since they're only ~140°." But never HOW much longer or how to determine how much longer. Please help this infrared sauna user! :)

Olive oil

people always talk about health benefits of olive oil but does this include cooking in olive oil as historically frying is seen as an “unhealthy” cooking method

Is a protein drink a good way to help meet your protein target?

What about protein drinks (mine usually is pro muscle milk) and protein powders to achieve your recommended levels of protein consumption for some of your more mature ;) LOL audience. I find getting to 1 gram per pound of body weight without protein supplementation is very difficult. Thank you.

Aspirin vs apixaban (Eliquis)

I listened with interest to your recent AMA that included your recommendations on aspirin therapy for heart attack and stroke prevention. I've been on aspirin "forever" for general stroke prevention but was switched to apixaban for a time after a catheter ablation for atrial flutter but then back to aspirin. Since I've gotten various recommendations recently from nothing to aspirin to apixaban, I'm very interested if you believe the same about apixaban as you do about aspirin. In full disclosure, I'm 81 years young which would put me in the don't take aspirin category in your table. Thank you for considering this as a topic.

Grounding/Earthing: Real or Snake Oil?

I have seen a lot of hype regarding Grounding/Earthing in the YouTube space, and the vast majority of videos are overwhelmingly in favor of it and make tons of health benefit claims ranging from the fantastical (cancer prevention, autism prevention) to more moderate (inflammation reduction, blood pressure reduction, sleep apnea prevention). Very few videos are critical of it. Is this real, or a heavily hyped health fad (assisted by algorithms, bots, amplification of survivor bias driving anecdotal testimonies)?

Visceral Fat

Help! I am 60 years old, a type 2 diabetic and I am working to get rid of the visceral fat, or better put, the big belly hanging on my body. I am lifting, cycling and walking consistently. I am also a cancer survivor, and I know I need to eliminate reduce visceral fat for my long term health. Should I do a long term fast? Is there a better way?

?

Do you actually look at all the questions? Because i mentioned in a previous question that im 16, and Peter still has been saying that he doesn’t think there are any adolescents who listen to the podcast

Hearing

What are some things to do/to avoid in order to maintain ear health

Smelly

Why do old people smell

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