C'mon - talk about pde5i
Lots of jokes there but tadalafil is likely a longevity drug that you ignore. Large anti inflammatory effect that has body wide benefits - indications reaching even to dementia. Just because it works for ED and prostate inflammation, and several other uses, doesn't mean it's trivial or for men only. Study up and report, please.
Alcohol and Cancer Risk
Recently, the Canadian Centre on Substance Use and Addiction published guidance to limit the number of alcoholic beverages to less than three per week. Part of the rationale behind this is that there is an increased risk for cancer at greater levels of weekly intake. I recall you mentioning several times on your podcasts the limitations of research on nutrition given its observational nature. What are your thoughts on reasonable amount of alcohol intake on a weekly basis, and the relative risk for adverse effects outside of the obvious ones.