Thrifty vs Spend Thrift metabolism
Hey Peter, on your recent AMA you indicated metabolism doesn’t have much of a genetic component. While I agree the biggest determinant of BMR is lean body mass, there’s a fair body of literature showing that how someone reacts to a caloric deficit or surplus varies significantly with some individuals increasing energy expenditure significantly with a caloric surplus and others decreasing energy expenditure significantly with a deficit. Dr.Eric Trexler out of UNC would be a great person to speak with on this topic. Just want to highlight an area you may not be familiar with.
Does a high protein diet in meats raise LDL-C?
I started to measure and consume a higher protein diet (mostly fish and chicken based) since March 2024, with a target of 120g per day. I weigh about 68kg, and does resistance training 3 times a week. My LDL-C was 117.34 in Feb 2024, and it went up to 141.7 mg/dL (3.67 mmol/L) when measured on 13 June 2024. I am on Atorvastatin 20mg since July 2023. My question is: does high protein diet raises LDL-C? This paper seems to imply so: https://pubmed.ncbi.nlm.nih.gov/31161217/.