Successful lifestyle-focus, precision medicine vs. marginal, dangerous, and expensive treatments for Alzheimer's Disease
I also upvoted another question, but personally I'm much more interested in the "multimodal" approaches, which I also hear are attracting the most attention and excitement at national Alzheimer's conferences. The following article details an intervention that is in the same mindset as Richard Isaacson's, and is worth some close attention. Reversing cognitive decline is now in the realm of possibility, as Dr. Isaacson has come close to demonstrating, and not surprisingly, it looks like it has been accomplished by this group: https://www.medrxiv.org/content/10.1101/2021.05.10.21256982v1
How do I thank you for the referral of Dr. Schmerin?
The question answers itself: thank you Peter. I was very moved by your Colorectral cancer screening article siting Chadwick Boseman's recent death. I booked an appointment with Dr. Schmerin, flew from Tucson to NYC, and had my first colonoscopy at age 70. Not that I have been remiss with my colon health - I have had 125 colon hydrotherapy sessions over the last 35 years. I can honestly say that it made me feel super healthy and I have not been really sick (I know, I know...so many health food people say this) in the last 3 decades. Dr. Schmerin and his staff are professional while down-to-earth; friendly while focused on making a patient's experience much more pleasant than in a hospital setting. I am so glad that you mentioned him in your article concerning the questions to ask a potential gastroenterologist who might provide your colonoscopy. Selah.
Podcast with Peter and DNS/stabilisation expert/ Beth Lewis?
Peter has posted a few Insta posts and podcasts in the last few months about "core" stability, "core" strength and how these impact on one's other exercise, workouts and daily living. Notable were the Beth Lewis and DNS guys (sorry his name escapes me) podcasts and pictures. Thank you for these podcasts and Insta posts, they have really made me re-think the importance of understanding and then implementing proper stability and flexibility. It would be great if Peter could do his take with visuals on how and why "core" stability and breathing matter. It is a message that, I'm learning later than I would have liked in life, should be understand and heard. It is not an airy-fairy concept made up by yoga and pilates people striking up mind-boggling poses ( though also not necessarily completely understood by them either). Peter will say he is no expert on this I'm sure but maybe with him explaining (as he does so well) in his own words in an AMA or with an expert (Beth Lewis?) together they can explain to us lay-ones the principles behind their thinking and why they are important. I think the words need to get out there... Regardless, thank you for making me think deeper and digging deeper.
mTOR spiking and exercise
Peter, you mentioned a vegan doctor who recently "shamed" you for advocating pre-exercise leucine supplementation because it spikes mTOR. On your podcast, you sneered at the doctor's apparent ignorance regarding acute vs chronic mTOR stimulation; yet, in today's AMA, you specifically make the point about how a once-daily postprandial glucose spike in an otherwise healthy person can contribute to long-term cardiovascular problems. Why wouldnt the same acute mTOR spike (via leucine supplementation) also have potentially negative health effects when repeated daily over months/years?