Best way sources of regularly getting summary statistics for my health?
What do you think are the most important summary statistics that capture the state of your health? If one were committed to regularly sampling the state of their body, what are the highest impact measurements one can make when weighed against the relative cost/invasiveness of the measurement, in terms of being predictive for longevity? Based on your podcast, it seems like the lipid panel done during most annual phsysicals is pretty interesting. Are there any others?
Insulin Resistance and Alzheimer's
Shulman mostly sidestepped insulin resistance and the brain, which apparently is more of a Glut-1, Glut-3 problem. Would love to know the mechanism there. Also, compensatory strategies including non-insulin dependent channels, enhancing lactate and ketone neural feeding (although exogenous ketones were ineffective in clinical trials for APOE4).