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NIMGU and Fasting

Peter — When you think about NIMGU, you've talked about how there are better and worse windows of time to eat post-workout. Is there a physiological difference in how NIMGU works if the post-workout meal breaks a fast of 12 hours, 18, 24, 36, 48 . . . + ? If so, what are / what do you guess are the important physiological characteristics that determine this difference? The 21-year-old college student writing this is a huge fan of your podcast — its breadth is unparalleled and the homework you do before each one benefits everyone who listens.

Any thoughts on nutrigenetics?

I stumbled across a company called Gene Food, which offers a nutrigenetic service to people. The customer can either purchase a DNA test (like they would at 23andMe) or they can import their 23andMe results. The company then provides a recommended diet for the customer based on their genes. What are your thoughts on nutrigenetics and how much trust do you think people should put into the recommendations of a company like Gene Food?

Your brain on statins

You and James O'Keefe discussed the possible cognitive effects of cholesterol lowering on the brain. Since lipophilic statins cross the BBB but hydrophilic statins do not, do you think the distinction here is important?

Cold water and cardiovascular disease progression

While I understand the “lack of evidence” and opportunity cost of cold water plunges I look at it from the perspective of fun and socialising with like minded people. Yet, I would like to minimise the risks related to it. What is your view of the quality of evidence in the studies below in relation to cardiac events and cardiovascular disease progression related to cold weather or cold exposure? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662093/ https://www.cell.com/cell-metabolism/fulltext/S1550-4131(13)00247-7

Exogenous ketones

What are your thoughts on using exogenous ketones for the purpose of supporting weight loss efforts or to help increase level of energy. Or what are any other options other than caffeine? If exogenous ketones are a good idea, what should be looked for On the label of a product to know we are getting something decent quality? Thanks Thanks