San Millan Assessment of Metabolic Flexibility
Why does Millan say in your podcast that zone to is characterized by a lactate level around 2? This threshold cannot be seen in his paper on the assessment of metabolic flexibility. Shouldn't it show up in figure 4? There are clearly several individuals maintaining relatively high-fat oxidation above 2 mmol of lactate in all groups. What am I missing here?
Cardiac drift during zone 2
Is there a cellular/ mitochondrial/ biochemical/ enzyme-related mechanism we know of that explains why heart rate can drift up after long bouts of zone 2? (E.g. Steven Seiler shows after 2-3 hours of low intensity "steady state" aerobic exercise, HR drifts up). Apparently it's not steady state, huh?
Weightlifting with Chiari Malformation
I have had CM since I was in high school and it has left my right side quite a bit weaker than my left side. I hear Peter talk about the importance of lifting weights especially as we get older. The problem I have is when I lift weights my left side will get stronger and build muscle but with my faulty wiring my right side does not gain muscle at all. This causes a significant imbalance. My question is should I just continue lifting weights and increase this imbalance or is there something else that might help with this imbalance?
Diving into menopause HRT and brain health
Requesting your evidence-based resources on long-term HRT. Doctors, while warming to HRT around menopause onset and for a few years afterwards, generally recommend stopping after about age 60, and it can be a battle to obtain HRT further along in menopause even if originally started in the recommended window. Thanks. Recommending this recent journal article, "Menopause hormone therapy significantly alters pathophysiological biomarkers of Alzheimer's disease", https://pubmed.ncbi.nlm.nih.gov/36218064/, be included in future episodes around Alzheimer's and around HRT after menopause.