HIIT benefits
For several years I trained with HIIT workouts and improved my overall fitness greatly. I added muscle during this time as the HITT I was doing included quite a bit of free weight lifting. Now, I have moved to focus on zone 2 training several days a week and free weights several days. I'm curious, from a longevity perspective, do you recommend HIIT training or suggest that is better left to those chasing other goals?
lymphoma and exercise
I'm currently undergoing treatment for large B cell lymphoma. I was told by my oncologist that I have little to no restriction in that if I feel good enough to exercise, just go for it. Do you recommend the same type of exercise during chemo (if one has the energy) as you advocate normally?
Medical Tourism
Tim Ferriss went to Mexico to get comprehensive text, at a discount, in his four hour body book. I'm turning 30 and going to mexico next month. What test would you recommend? I'd like a snapshot of my health now so I can better understand any future problems. I'm perfectly healthy, please list the important ones and then the nice to have stuff. Also, what is you opinion on elective surgeries there? I'm considering PRK after your recent podcast on the eye.
Monogenic Diabetes
Hello Peter & co., In my family there is a high prevalence of monogenic diabetes, MODY 2 aka GCK-MODY, in particular. Tough rare, I think it is the most common among the monogenic. Few days ago having dinner with my uncles (75-85 years old) they are all being treated of T2DM and I got so frustrated...in the other hand, they were so happy with their metformin, SGLT2...and really looked so young being really old (It's kind of scary) Why such a different different type of diseases are under the umbrella of the same name? and even more, why did someone put even the same number to the disease? (diabetes, 2) In Mody 2 there is just a time displacement in the detection of glucose level but I supose none of the underlying mechanisms of insulin resistance are present at all. Maybe less capacity of glycogen storage and more prone to ketosis due to the blindness to glucose by defective or scarce GCK. Here in Spain treatments are free and a wrong diagnostic can provide you a metformin prescription (not bad), but the burden regarding to insurance policies should not be considered to be applied to this group at all. Some studies give us some kind of protective counterregulatory mechanisms against cardiovascular problems https://www.sciencedirect.com/science/article/pii/S2213231721000033?via%3Dihub So, what are your thoughts about this kind of mismatch between so well established basic science and so bad clinical interpretations of it. Maybe is an European or Spanish problem but I suppose it is not. Thank you