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Kratom as an alcohol substitute?

My wife recently quit drinking alcohol - which I’m very proud of her for. One of the “wellness” blogs she reads recommends a Kratom tincture as an alcohol substitute. There seems to be some cardiotoxicity associated with Kratom but I’d love to hear your take on it. Thanks Peter!

kids' health

I would love to hear more about ways to optimize our kids' health- diet, supplements, what to measure/discuss with their doctor, etc.

Pterostilbene vs. Resveratrol for AD prevention

Hi, I am a long time listener to your podcast and really appreciate the information and knowledge you are disseminating to the public. Thank you. I am laser focused on AD prevention and have run across a few papers recently on Pterostilbene vs. Resveratrol for AD prevention (as well as other reasons). Do you have any opinion on Pterostilbene use vs. resveratrol? Given what I have read about the bioavailability of Pterostilbene it would appear to be superior to resveratrol but I'm' wondering what I am missing. Thank you and I appreciate all you do for society.

Balancing weight as a 40yr old racing masters cyclist.

As a 40yr old amateur masters cyclist who competes, how do I balance being healthy with lean muscle mass for longevity vs being lightweight enough to be competitive whilst not negatively impacting longevity. I'm a big fan of a Polarized training model with %80 zone1 & 2 .. and %20 vo2max + work. As a Crit racer I understand being lightweight is not as important, but there are times I like to compete in Road races where weight matters. As someone who is turning 40 this year, I want to be healthy and have muscle .. whilst also enjoying being competitive on the bike. I currently do 2 strength workouts per week (focusing on strength and not hypotrophy) whilst doing 10-15 hrs some weeks on the bike if time permits. Any help on how to find balance on this topic would be great.

How can calorie restricted diet be sustainable?

I have heard a lot that the best way to lengthen lifespan is to do a caloric restricted diet. It makes sense to me when someone starts out overweight, e.g. if you start out 50 lbs overweight, you can spend a decade or so, slowly losing weight through a calorie restricted diet and that would be a good thing. But I'm 5'ft 2in and weight 112 lbs. I consider my weight to be ideal (would you agree or disagree?) If I did a calorie restricted diet for a few years and lost 10 lbs, I would be underweight. If I did it longer, I would be anorexic. How is a calorie restricted diet for someone that has an ideal weight sustainable?