Cardiovascular health & diet
My husband is a 44-year-old with high cardiovascular risk. I've been absorbing all of your content on heart disease and hypertension, and am still having a hard time answering the question, What is the best diet to lower blood pressure and reduce ApoB? His primary care doctor has been thoroughly useless, and I'm trying to sift through a vast amount of contradictory dietary recommendations. For example, are fruits good because they're high in fiber, or bad because they are high in fructose? Is plant-based better, and if so, which plant foods are generating this difference, and is this because of removing saturated fats, increasing specific nutrients, or some other mechanism? Are grains bad because they're processed, or good because they have soluble fiber? How big a culprit are industrial seed oils and/or lack of omega-3? How quickly should one see results from dietary interventions? Bottom line: If you're already exercising, sleeping well, and a non-smoker, what are the biggest dietary and/or lifestyle changes that will move you into a lower risk category? Thank you so much for providing a exceptional resource of such genuineness and rigor.
AMA (probably a series) centered on patients and their lab studies
Could you do an entire AMA discussing more patient lab/diagnostic studies with your interpretations and approach to treatment of patients. Love when you show the Boston Diagnostic Lab reporting data, including the "Cholesterol Balance" charts. Particularly interested in what causes low Lathosterol with sky high Demosterol in a cholesterol hyperabsorber treated only with a statin?
Anemia
Currently mild MDS diagnosed thru genetic testing & chronic anemia (10-12% below normal red blood cell count). Causation likely from receiving CHOP 20 yrs ago. I'm a 71 yr old avid road cyclist & also longtime resistance trainer. Is there any supplementation & training methods that can better utilize oxygen uptake in muscles with the healthy red blood cells that I do have available. My hematologist is reluctant to use EPO at this point because of cardio risks. Thank You
Incorporating zone 2 & zone 5 into an already existing strength programme.
Hi Peter, Firstly, thank you for researching longevity and presenting it in such a meaningful way. I have recently started incorporating zone 2 training (stationary cycling) at a dose of 4 x 60mins per week and 1 x zone 5 session (4 x 4 protocol) in combination with an already existing 3 strength sessions. As I don't use a lactate meter, I use PRE and the MAF method to determine heart rate that hopefully places me in zone 2. A common belief is that an aerobic base should be built first before incorporating strength and vo2 max training. My question is: Should I build an aerobic base first using exclusively zone 2 training, or will I still get the same benefits to cell health incorporating zone 2 into an already existing strength program? Much appreciated
Statin or HRT for women with high ApoB?
I just finished listening to your AMA on ASCVD. Kudos to you for your clear explanation regarding how this disease develops as well as how to best ascertain our risk. I am, however, still confused about how women can best manage a high ApoB. Is this through a statin or are you in agreement with your former podcast guests Dr. Bluming and Dr. Tavris who suggest HRT, instead of a statin. Like others here, I would like to know more about treatment, especially for women, given that Dr. Roberts, quoted in Estrogen Matters, says that statins are not helpful for women. Specifically, what would you suggest for a woman with a ApoB score in the low 100s? Thank you!