Drifting out of Zone 2
If you drift out of Zone 2 (lactate ~3 mmol/L) during an exercise session do your muscle cells switch completely away from fat-based mitochondrial energy production or are your muscle cell mitochondria still operating at maximum capacity and you’re cells are just topping off with other energy sources?
Leptin resistance - How to address, overcome?
Can you give some good, actionable tips for dealing with and overcoming leptin resistance? Thank you and I appreciate all you do. I’m incredibly hungry all the time and to date have been successful in the battle to stay reasonably lean and fit, but the day is coming where I better have my ducks in a row. I can’t out-exercise this forever.
The Straight Dope on Cholesterol - Part X?
You closed Part IX of the series with this statement: I would like to address one additional topic in this series before wrapping it up – the role of pharmacologic intervention in the treatment and prevention of atherosclerotic disease, so please hold off on questions pertaining to this topic for now. Can you please point me to where this content is? I don't see a Part X linked to the series. Thx for your help here.
Vegan or vegetarian for heath and longevity.
I know that you are neither vegan or vegetarian and maybe I should take some cues from this. I have listened to all your podcasts about diet. I have seen your blog posts about red meat. I am aware that most of the "science" behind this is epidemiological in nature. I know you have a special and unique ability to do resarch and I believe there is something, maybe even more than something to this. I was really hoping for a podcast or ama related to this. On a side note, I was always confused by your conversation with bill harris as to why epa/dha supplementation from algea never came up. He even mentioned the ecological toll coming from fishing but no mention of marine epa/dha alternatives to salmon, it was a head scratcher for sure.