Ask Me Anything

with The Peter Attia Drive - Private Subscriber Feed

Subscribe to ask a question

TAG/cholesterol proportion inside the lipoproteins

Is it correct to say that a TAG excess in liver increases VLDL-P, VLDL-C, LDL-P and LDL-C? If so, why is there an increase in cholesterol levels? In a first glance, one would guess that the amount of cholesterol required to make membranes and hormones shouldn’t be related to TAG needs. Is it because more cholesterol must be produced to maintain the TAG/cholesterol proportion inside the lipoproteins?

Statins and eventual excess of TAGs and phospholipids

Given that statins reduce the amount of LDL vehicles by reducing the production of one of its passengers (cholesterol), what happens to the other passengers that would need to use that same vehicle? I'm talking about TAGs and phospholipids. Their amount didn't change, so they still need as much vehicles as they needed before. As they won’t have it, where does the excess of TAGs and phospholipids go?

Changes in metabolism after zone 2 exercises

Do zone 2 exercises make the body more able to remain in the aerobic pathway just by an increase in mitochondrial density? Or is it also necessary to upregulate pyruvate dehydrogenase?

zone 5 vs. zone 2

What are the metabolic adaptations that will come from a zone 5 exercise, that will never come from a zone 2 exercise? (And vice versa). Would a zone 3 exercise bring some of both, or nether of both?

zone 5 vs. HIIT

Are the benefits from a zone 5 exercise the same as the ones from HIIT?