Your show notes are great, especially the links and pictures. Have you ever considered producing a glossary for your website? Something that defines things like Topo Chico, ATP, ADP, AMPK, mTORC1, Chylomicron, VLDL, LDL, IDL, GLUT4, GLUT2, Acetyl-CoA, fructokinase, metformin, rapamycin, etc. that link to the existing show notes for the most relevant show. Searches tend to pull up lots of pages that aren't as relevant as others, so such a glossary would get members to the best place fast. This would also tend to make google searches better.
I am a newer member and first submitted question. 55Y.O healthy male with 54 YO wife with few autoimmune challenges. My question listening to your discussion with Dr. San Millan is considering if any of the subjects that have been evaluated are female? I am a recreational cyclist, and self test all the time, and generally get positive outcomes from ideas I hear on this podcast and others, but my wife has negative outcomes when I share my ideas with her. But this discussion, like most others, are not looking at the female athlete, or females in general. So, my request is that on your follow up, include information on the effects of zone 2, diet changes, DM, and other aspects from the female perspective. In general, Dr. Attia- do you have a female colleague or expert that self-tests and explores longevity as much as you? Thanks for your excellent work and for sharing so much of your expertise.
Is it beneficial for a diabetic person to have less mitochondria then normal, so they remain as much as possible in the lactate anaerobic pathway? That pathway takes more glucose from the blood than the aerobic pathway. Don’t we want to take the glucose out of their blood?
Do muscles need insulin to take glucose from the blood during exercise? Or is the body able to get all the glucose it needs via the insulin independent pathway? I ask that because an insulin dependent glut4 would certainly help to feed the muscles, but it seems weird to see insulin in the blood during exercise. It would promote fat and glycogen storage in a situation where storage is detrimental.