In reference to your latest posting about the concerns about a ketogenic diet, I think a bit of clarification would be good. Many people blend low-carb diets, say less than 150g of carbs per day, into a ketogenic diet. Whereas a ketogenic diet is a diet that brings the body into ketosis, with a general considered threshold of <20g of carbs per day, although that threshold could be much lower for some individuals. Clearly near 0g of carbs has the potential to negatively effect some phenotypes. But let's turn this problem on its head. Is there a carb limit where we can unconditionally say that the carb intake is unreasonable or unneccesary? How many carbs is too many carbs? Yes, I realize this gets tricky with elite athletes because of their utilization rate and they will have an hourly intake rate limitation (40g to 300g+ per hour) that effectively caps their carb energy calories per day.
Much has been said about how fast we lose strength and mass when forced into a sedentary period, as in bedridden from injury. Assuming the person in question is male and in good shape, what could he do to maintain the state of his body? Maybe Vitamin E (10.1055/s-2007-972612), but what about Metformin, TRT, etc? Would interventions that inhibit cell growth also inhibit the rate of atrophy? Plainly, is there something helps to pause the current state of your physique?