I’m guessing that you use the Cleveland heartlab. Boston Heart does not have many of the assays you and dayspring talk about. I’m a new member, I’ve started at podcast #1 and working forward. Very much enjoying the technical content. Had,to listen to the dayspring series 4 times … no longer ordering Boston heart. I’m very focused on endothelial health .. literature says eGFR an analogue for SDMA ?? I’d this true ? I’m going back on zetia after the dayspring shows. ApoB slightly elevated.
A lot of us are taking NAD+ precursors (NR and/or NMN). Prof Sinclair has mentioned several times these supplements must be refrigerated and suffer from substantial instability. Worse, he has said these supplements degrade into nicotinamide. Unfortunately his cryptic comments about supplement instability have not been accompanied by any sort of published scientific support. This has resulted in a surge for "stabilized"(?) forms of these supplements that are sold as expensive, celebrity backed name-brands (see, for example, Prof Guarante's products). My questions are: has NMN/NR supplement stability been studied somewhere? What are the chemical reactions that cause the supplement degradation? How unstable are really these supplements? What methods are used to "stabilize" these products?
One of the most unpleasant side effects of aging for most men is benign prostatic hyperplasia (BPH). My question is: what is Peter's opinion of PAE when dealing with BPH? Sounds like something with significantly lower risks and side effects than anything else available.
If you had to prioritize the top 5 health markers everyone should know about themselves could you provide a list? Maybe break into Male/Female if needed? Maybe add a couple of additional ones based on the age of the person being tested? Listening to your podcast I assume one would be a glucose tolerance test, maybe a DEXA scan but can you list the others that hands down have to be documented and understood before any health plan (framework) or intervention can be formulated?