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Low dose daily aspirin risks and benefits

What group or groups do you recommend take low dose daily aspirin? What are the risks and benefits?

Blood Pressure - familial? essential? What are other non-insulin resistant causes?? What can be done to mitigate?

I'm a 68 year old gal, recently needed to add 3rd med to control BP )-: Have good cholesterol numbers, low triglycerides and after wearing a CGM for 2 months have low glucose - avg = 78, most days don't go much over 100. Very top was 150 on my 10.12.53 bday (cake and alcohol twice that day (-;). Recent ca++ scan shows zero plaques. Started daily exercise 3 months ago (based on your recommend - zone 2 + weight training, HIIT, tennis or GF longer walk almost daily) along with low carb (almost no alcohol,1-2x/month), TRE (13-15 hr/day) diet to see what I could mitigate. So far lost 5 lbs able to cut just one med in half. But if I'm not insulin resistant, what's going on with my bp? I'm -5'4" smaller framed, weigh 135 lbs. now but was 115 in high school. I'd like to get to 125 but am focused on building muscle. Fam History: My never too heavy nurse mom took BP meds from about 45 yrs on as have I. She died at 72 from CMML. Her father died of unknown cause cerebral event in mid 40's (1926 no autopsy). Have 69 year old trauma surgeon brother who races bikes - no meds. Had homeless brother who died of massive coronary at 58 - autopsy showed extensive coronary disease. Beside CGM, am wearing OURA recently working on sleep improvement which is NEVER past 7 hours of sleep even though 9 hours in bed. I'd like to understand and improve BP issue - what else could I do to get off meds? What is the blood pressure monitor you recommend? Would high school weight be helpful or unhealthy?

Glucose utilization in insulin resistance

I am wondering if we have any data regarding how effectively people with diabetes/insulin resistance can drop their glucose levels vs those who are insulin sensitive through exercise? When I wear a CGM, being insulin sensitive, I'm able to prevent my blood sugars from spiking quite effectively from moderate intensity exercise following a meal. However, I would presume that those with diabetes would have a more difficult process doing this through exercise for multiple reasons [ex. insulin deficiency, insulin resistance, lack of metabolic flexibility, lack of mitochondria, etc]. Any thoughts would be appreciated.

Rapamycin before covid vaccine?

What are your thoughts on a course of rapamycin before getting the covid vaccine/booster like in that flu vaccine study which showed a boost in immune response?

PVCs during exercise

Do PVCs that occur during exercise increase long-term mortality?