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Neuroprotective for ALzheimer's? APOE3 Jackson variant

Implications of APOE3 Jackson variant, protective for Alzheimer's Disease, for diet and drug development

Beta Alanine for endurance sports

Hi - firstly, thanks for an awesome site and podcast! I'm interested to know more about Beta Alanine and the effect supplementation may have on lactate production and threshold in muscles. Would supplementation enhance performance over a maximum 1 hour effort. Thanks!

Fiber

Is fiber important in the diet? If so, in what ways?

MTHFR

If someone has MTHFR mutations, are there any general recommendations you give? Or are there specific recommendations based on signs, symptoms, or other test results?

Leptin and Ghrelin

I'd love to hear more about leptin and ghrelin, especially, if a better understanding of them in general (or in the context of an individual) could provide any actionable insights regarding lifestyle.