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17

Rapamycin: Idiot's guide to obtain, prepare and ingest 5 mg rapamycin once a week, 8 on, 5 off?

How to obtain, prepare and take 5 mg rapamycin once a week, 8 on, 5 off? I am a healthy 65 year old male in San Diego.

1

What to take before carbohydrate loading?

What supplement is best to take before a meal... that the sugar would not rise too much?

4

The regulation of healthspan and lifespan by dietary amino acids

We've heard a lot of guests promoting carbohydrate restriction, but what about all the research demonstrating benefits of protein restriction, especially certain amino acids? Is this an unconscious bias? Here's a good recent review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277109/

2

Suggested Guest - Maria Mountain

The importance in maintaining stability and core strength have been discussed many times... as has Bob's interest in Hockey goalies! I am not a goalie but use this exercise physiologist's training routines... Maria Mountain - trained recent CDN gold medalist in decathlon I thought her latest video on training the aging athlete is IMO perfect for discussion - not sure if your site blocks URLs hence the extra spaces... www.youtube .com/watch?v=NjeoXjN-mvQ

3

Immune Exhaustion: T-Cells and B-Cells - Related to sars-cov-2

I've seen recent studies showing immune exhaustion of T-Cells and the negative effect of having too much viral load. Curious what the long term implications of that is for future contraction of sars-cov-2. Scenario: Native Contraction followed up by 2 shots of Moderna or Pfizer. After native contraction could the recommended dose be just 1 shot to prevent immune exhaustion of T-Cells or B-Cells?