Somatostatin's role in metabolism and how Peter thinks about it for his patients
It seems like somatostatin acts as a brake on various metabolic processes by suppressing GH, TSH, digestion, glucagon, and insulin release. Given the fact that Peter has discussed insulin and glucagon many times, it seems worthwhile to explore a hidden player in that antagonistic interplay: somatostatin. I think there's enough material in the following bucket to warrant an entire episode: "Regulatory molecules important to metabolism that are NOT insulin, glucagon, or glucose/fructose." Examples include PYY, orexin, leptin, T3/T4.
High Cholesterol Normal Heart Scan
Family history Father died at 60 of a heart attack, his Father died at 49 of a heart attack. I am 61 My cholesterol has been increasing 10 points a year and is currently 290, also high triglycerides. I took statins for 5 years and they worked well with no problems. In 2016 I had a 64 slice heart scan and my arteries were normal. The cardiologist told me to stop taking my statins, I did not need them. This was supported by my internist, with everything I read it seems contrary to the advice I received. Your thoughts?