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2

Are you aware of whether collagen worsens Dupuytren's contracture?

I have developed mild Dupuytren's contracture on the palms of both hands. I joined a couple of online groups consisting of thousands of people who also have this condition. There are some people on there quite knowledgeable around nutrition and other issues connected to this, and many that seem to be spreading quite alarming information. There have been many posts warning about taking collagen supplements. In some recent posts in the group, things along the lines of this have been said: "It depends on the collagen supplements. I take a type 2 collagen which helps with hair, nails and skin as well as joints and muscles. The type of collagen that we produce too much of is Type 1 and 3 which as far as I know you can't get in a supplement. Their the repair collagen made in the body." Many people claim that vitamin C worsens the condition, such as the following claim: "Vitamin C stimulates collagen and scar production in the body, so taking extra vitamin C for a cold or flu for instance could theoretically worsen your Dupuytren's or Ledderhose." It is hard to know what might have some accuracy in it and what is garbage. Do you have any knowledge around this area, and whether collagen and/or vitamin c supplements may worsen this condition?

6

Taubes (and Fung, Hallberg) vs. Norton

Peter you recently had Layne Norton on your show whose viewpoint seems to be diametrically opposed to many of your other guests with regard to metabolism (calories vs hormones), and I felt that surprisingly you were tougher on Taubes than Norton when you where challenging his viewpoint. Can you explain how you reconcile the hormone evidence vs the calorie evidence personally and with your patients?

5

Trazodone for sleep

In all of your various commentary on sleep, I have never heard you mention Trazodone as an aid. For many people evidently, the increase in serotonin is the key to a good night's sleep. I'm curious to know your take. Do you prescribe it? Have you taken it yourself?

2

Hadza v western and caloric requirments (https://pubmed.ncbi.nlm.nih.gov/22848382/)

Can you do and AMA on Herman Pontzer's findings. Primarily the equal caloric needs of hunter gatherers vs western society. Why? What other questions does this create? Is this surprising to you?

4

Heart rate

I'm a 52 year old menopausal woman. My resting heart rate is regularly between 47-55. When I exercise- I do lots of hiking- it very quickly gets to 160-168bpm. I am winded during this but can still continue. When I'm finished my heart rate comes down pretty quickly(within 2 minutes). Is this ok?