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Cancer “long-read” technology

Hi Peter, Can you share with us your knowledge around “long-read” technology (Oxford Nanopore) vs Short Read (Illumina), specifically around which cancers can currently be screened by it, which companies are providing cancer sufferers this service, and how you view developments in this technology over the next 3 -5 years. Thank you

Medium chain TGs for the prevention or treatment of MCI and AD

Can you please review the effectiveness of MCTs for preventing and treating MCI and early AD in apoE4 - and apoE4 + people. Thanks!

podcasts planning to warn us about statins and BP meds

I got a promotion to listen to this and don't want to join his site and listen for the answer. I am pasting in here some of what he wrote to promote his webinar. He is scaring us about certain med. What do you know about this?: "Instead, it's my exclusive interview with one of the world's most prominent and respected pharmaceutical industry insiders. His name is John Abramson, MD. He's been on the Harvard Medical School faculty for 16 years, has served as a family physician for 22 years, and has had over 65 national media appearances. He serves as a consulting expert in litigation involving the pharmaceutical industry -- including to the FBI and U.S. Department of Justice. I can also tell you personally that, beyond being brilliant and truly courageous (you'll understand exactly what I mean), he's a deeply caring and wonderful human being. And in my first interview on January 17 in Live Long & THRIVE, Dr. Abramson is going to reveal deep insider FACTS about prescription drugs I can assure you that you don't yet know. I can also assure you that MOST doctors don't know this, which as you'll understand is a very big and truly dangerous part of the problem. Most importantly, I can assure you that you -- and everyone, considering 66% of all people in the U.S. alone use prescription drugs -- need and deserve to know what Dr. Abramson will reveal. By the way, these are not some concerning facts you may already know about pharmaceuticals, such as that medical mistakes -- including errors in the use of prescription drugs -- are now the 3rd leading cause of death in the U.S. It's actually far MORE concerning than that -- and it is sincerely vital if you now take or may ever take statins, blood pressure meds, proton pump inhibitors, diabetes meds, pain meds or ANY type of prescription at all.

meclizine and dementia risk

I found your interview with Rich Miller most interesting. Although meclizine produced positive results in the ITP, isn't this drug also associated with increased dementia risks do to it's anticholinergic activity?

Fructose

I listened to robert lustig on the huberman lab podcast. Discussed irreversible binding of fructose to AMP kinase and 2 lipid enzymes. Discussed binding in endothelium disrupting tight junctions. No mention of phosphate depletion and uric acid pathways touted by rick Johnson. No good references about this noted. Are they both right, or is one of them pulling the wool over our eyes?