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Is keto causing lowered immunoglobulin (esp. IgG)?

My partner donates blood plasma regularly. She is also following a ketogenic diet since at least five years and often falls (supported by the lack of hunger) into an intermittent fasting protocol. During a recent regular check-up at the plasma donation center she was told that her IgG-levels are too low to donate plasma on a weekly basis, which she used to do before without problems. Can following a ketogenic diet (long term) cause lowered immunoglobulin levels in serum? What would the mechanism be and how can this potentially be prevented? Is it possibly linked to the increase in γδ T cells? (Goldberg et. al., 2019) Bluntly theorized: More T cells eradicate admitted antigens more efficiently, which reduces the requirement for the—I presume—somewhat delayed B cell response and by that lowering the production of IgG?

Knee and hip pain prevention

Dear Peter, can you do an episode on knee and hip related issues and other age related skeletal related pains (hip, knee, wrist). How to prevent them, things that can be done other than surgery, i.e. exercise. In Tim’s Titans book you had an exercise laid out for strengthening ones muscles around the knee. Along those lines since you mentioned a few times how losing function and preventing the loss of mobility is a really important thing in order to extend life and health span (picking up a toddler grandchild from the floor when 80 etc.). Thank you.

How to best deal with arthritis (knee)?

Three years ago I felt a lasting pain in my knee and was diagnosed with arthritis. I'm just in my 30s and apparently it's a mix of various factors that caused it: shorter leg, one heavy impact, post-surgery scaring that creates tension, slightly twisted femoral neck etc. I'm taking glucosamine and chondroitin along with MSM and have stopped lifting heavy. Yet the crunching noise/feeling in my knee remains and so does the constant mild pain. What can I do better to mitigate and prevent further impairment?

Peptides

Thoughts on peptide therapy

Watching Senate hearing on Ivermecti

I am watching doctors passionately report to Senator Johnson, committee chairman, regarding Ivermectin. It appears we have a structural flaw in the system. It's focusing on NIH. They are so focused on new drugs that little effort is being made to study existing drugs. The doctors are understandably angry. I hope you are watching this. It's live now on Bloomberg. I gather from observation that you are only going to interview established doctors and related research. Dr. Pierre Kory, frankly, chewed them out. This time they are listening. Dr. Kory has results from 11 randomized controlled trials. He's asking NIH to pick up the studies and review it. This time I think Senator Johnson will. He said he will send a letter to NIH as soon as this hearing is over. I looked him up. Looks like he heads a committee related to Homeland Security. I hope you are watching.